Burnout has been around for about half a century as a metaphor that refers to a psychological state that is characterized by mental exhaustion. Meanwhile, a myriad of scientific publications has appeared, not to mention the attention burnout received in the popular press. To date, over 18 thousand peer-reviewed papers on the burnout have been published. Despite this overwhelming number of scholarly publications some issues are still hotly debated. This chapter seeks to answer six burning questions that still haunt burnout research: (1) what is the nature of burnout? (2) Is burnout a medical diagnosis? (3) How to assess burnout? (4) is there a burnout pandemic? (5) Is burnout rooted in the person and the body? 65) Are burnout interventions successful? The chapter closes with an outlook and reviews avenues of future research.