There is a growing interest in developing resilience-building programs in the work context. Yet the resilience literature provides no clear answer about what constitutes such a program. This article presents a set of criteria for resilience-building programs. We developed these criteria by systematically reviewing studies that synthesized the evidence about the definition, conceptualization, measurement, and enhancement of psychological resilience. A literature search resulted in 286 hits, of which 21 studies met our inclusion criteria. Based on our review a checklist emerged of 12 criteria for resilience-building programs which include: specify which working population is in need of psychological resilience; specify which definition of resilience is being used; display and explain the process that people go through in order to adapt to adversity; describe how resilience will be measured and enhanced as a dynamic process, as well as say which type of positive adaptation—to which adversity, in which work context, and when—is involved; and make clear the starting point and purpose of the work. These criteria can be regarded as a valuable navigation tool in the complex field of resilience: Program developers can use them to optimize the content of resilience-building programs and to ensure that relevant information is reported; reviewers of resilience-building programs can use them to analyze, evaluate, and compare programs. Therefore, the checklist could become an indispensable tool for both researchers and practitioners to improve designing, describing, and reviewing resilience-building programs at work (download article).